产品货号：
Z16196
中文名称：
FRMPD1抗体
英文名称：
Anti-FRMPD1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FRMPD1 Antibody |
| 指标别名 | FRMD2,FRMD2,KIAA0967,FERM and PDZ domain-containing protein 1,FERM domain-containing protein 2 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,IF |
| 基因名称 | FRMPD1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | FRMPD1 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human FRMPD1.The immunogen is located within amino acids 1330 - 1380 of FRMPD1. |
| 计算分子量 | 173kDa |
| 成分 | FRMPD1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | FRMPD1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The FERM and PDZ domain containing (FRMPD) protein family consists of four proteins that contain a FERM (Four-point-one,erzin,radixin,moesin) domain and at least one PDZ (PSD-95/Discs large/Zonula-occuldens-1) domain.FRMPD1 was initially identified through a yeast two-hybrid screening with Activator of G-protein signaling 3 (AGS3),a protein that acts to stabilize the GDP-bound conformation of Gai,as the bait.FRMPD1 binds to the tetratricopeptide repeat of AGS3 and stabilizes AGS3 in a membrane environment.Suppression of FRMPD1 in Cath.a-differentiated neuronal cells decreased the level of endogenous AGS3 in membrane fractions by~50% and enhanced the inhibition of forskolin-induced increases in cAMP.Co-immunoprecipitation studies indicate that the interaction of AGS3 with FRMPD1 is mutually exclusive with the interaction of AGS3 with Gai3,suggesting that FRMPD1 may position AGS3 in the membrane where it can then interact with Galphai. |
| Uniprot ID | Q5SYB0 |
| 基因名全称 | FERM and PDZ domain containing 1 |
| 蛋白名全称 | FERM and PDZ domain containing 1 |
| 推荐稀释比 | FRMPD1 antibody can be used for detection of FRMPD1 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunoflourescence starting at 20μg/mL.For immunofluorescence start at 5μg/mL.Antibody validated:Western Blot in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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